Cognitive function in patients with chronic pain treated with opioids: characteristics and associated factors
| Autor: | M.M. Jørgensen, Geana Paula Kurita, Per Sjøgren, Per Rotbøll Nielsen, Jette Højsted, C. A. De Mattos Pimenta, P.E. Braga, L. Frich |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
business.industry Neuropsychology Chronic pain Cognition General Medicine medicine.disease Cognitive test Anesthesiology and Pain Medicine Finger tapping medicine Memory span Physical therapy Anxiety Effects of sleep deprivation on cognitive performance medicine.symptom business |
| Zdroj: | Acta Anaesthesiologica Scandinavica. 56:1257-1266 |
| ISSN: | 0001-5172 |
| DOI: | 10.1111/j.1399-6576.2012.02760.x |
| Popis: | Background The paucity of studies regarding cognitive function in patients with chronic pain, and growing evidence regarding the cognitive effects of pain and opioids on cognitive function prompted us to assess cognition via neuropsychological measurement in patients with chronic non-cancer pain treated with opioids. Methods In this cross-sectional study, 49 patients were assessed by Continuous Reaction Time, Finger Tapping, Digit Span, Trail Making Test-B and Mini-mental State Examination tests. Linear regressions were applied. Results Patients scored poorly in the Trail Making Test-B (mean = 107.6 s, SD = 61.0, cut-off = 91 s); and adequately on all other tests. Several associations among independent variables and cognitive tests were observed. In the multiple regression analyses, the variables associated with statistically significant poor cognitive performance were female sex, higher age, lower annual income, lower schooling, anxiety, depression, tiredness, lower opioid dose, and more than 5 h of sleep the night before assessment (P |
| Databáze: | OpenAIRE |
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