Synthesis of a Series of Novel Chiral Aromatic Heterocyclic Macrocycles Containing L-Amino Acid and 2,5-Bisphenyl-1,3,4-triazole Subunits
Autor: | Hong‐Wu Zhao, Wen-Ting Hua, Wei Yang, Rugang Zhong, Hong Yan, Jin Cui |
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Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Synthetic Communications. 39:3038-3044 |
ISSN: | 1532-2432 0039-7911 |
DOI: | 10.1080/00397910902730879 |
Popis: | An array of novel chiral aromatic heterocyclic macrocycles, which may show potential enantiomeric recognition to variable D- and L-amino acids, were synthesized in acceptable yield. The desired macrocycles 3a–c and 4a–c were obtained via the condensation reaction of chiral diamine intermediates 2a–c with 2,5-bis(o-chloroformylphenyl)-1,3,4-triazole 5 in a presence of Et3N in a highly diluted dichloromethane solution at room temperature. |
Databáze: | OpenAIRE |
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