Physiological assessment of autohemoperfusion through activated charcoal

Autor: V. G. Nikolaev, V. G. Aleinikov, S. L. Medvedev, I. S. Mudraya, V. I. Galinskaya
Rok vydání: 1977
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 84:1684-1687
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00804806
Popis: The adsorptive properties of phenolformaldehyde-activated charcoal with respect to physiologically active substances were studied after static conditions (adsorption from physiological saline) and during autohemoperfusion of the limb vessels at constant rate in experimental animals. Phenolformaldehyde-activated charcoal was found to adsorb serotonin adrenalin, noradrenalin actively and histamine to a lesser degree from physiological saline. Activated charcoal readily adsorbed serotonin, adrenalin, noradrenalin, and acetylcholine histamine less readily, and papaverine only very slightly from flowing blood. When the column of charcoal adsorbent was connected to a main vessel of the animal no changes were observed in the systemic blood pressure, but in some cases the perfusion pressure fell on account of a decrease in the resistance of the vessels studied.
Databáze: OpenAIRE