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Purpose: Retinoblastoma is the most frequent intraocular neoplasm of childhood. While survival rates, globe salvage, and disease stage at presentation have significantly improved in the last decades in high-income countries (HICs), retinoblastoma remains a clinical challenge in low and middle-income countries (LMICs). Furthermore, novel therapies such as intraarterial chemotherapy (IAC) are often unavailable, or underused, in middle or low-income countries. Methods: We present a retrospective case series, where we examine the outcomes of 6 eyes in 6 patients who received IAC as primary, or secondary, therapy for retinoblastoma. Results: Four eyes resulted in disease remission, while two ultimately were enucleated due to ophthalmic artery anatomic issues. Nevertheless, all patients remain disease free at last follow-up. Conclusion: Intraarterial chemotherapy is a safe and effective alternative for treating retinoblastoma. Unfortunately, due to disparity in healthcare access between different socioeconomic strata, it is not a common therapy in Mexico. Further work needs to be undertaken, such as increasing awareness of this disease, inter-institutional twinning, and overall improvement in healthcare access. |
