Diastereoselective additions of lithiated N-tertbutyldiphenylsilyl- S-methyl-S-phenylsulfoximine to imines and aldehydes

Autor:	Stephen G. Pyne, B. Dikic
Rok vydání:	1990
Předmět:	Steric effects chemistry.chemical_classification Addition reaction Organic Chemistry Imine Substituent Diastereomer Biochemistry Aldehyde Adduct chemistry.chemical_compound chemistry Drug Discovery Organic chemistry
Zdroj:	Tetrahedron Letters. 31:5231-5234
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)97851-1
Popis:	Lithiated N-tert-butyldiphenylsilyl-S-methyl-S-phenylsulfoximine undergoes 1,2 addition to imines (R 1 CHNPh) and aldehydes (RCHO) to give diastereomeric adducts. The diastereoselection of the former reactions is dependent on the steric demand of the imine substituent R 1 , while that of the latter is independent of the steric demand of the aldehyde substituent R.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8f9d772fed12b3d571de4ccf8fad9a9c https://doi.org/10.1016/s0040-4039(00)97851-1 Zobrazit plný text záznamu