STRUCTURAL AND FUNCTIONAL CHANGES IN THE LUNG AND HEART TISSUES IN RATS AFTER EXPERIMENTAL INTRAUTERINE HYPOXIA OF DIFFERENT SEVERITY

Autor:	K. V. Rozova, L. I. Shevchenko, O. I. Zhdanovich
Rok vydání:	2015
Předmět:	medicine.medical_specialty Lungs tissues business.industry Hypoxia (medical) Intrauterine hypoxia medicine.disease Endocrinology Internal medicine medicine Tissue hypoxia Thickening medicine.symptom Lung tissue business
Zdroj:	Neonatology, surgery and perinatal medicine. 5:16-22
ISSN:	2413-4260 2226-1230
DOI:	10.24061/2413-4260.v.2.16.2015.3
Popis:	In studies on the monthly rat pups who had undergone by intrauterine experimental hypoxia of varying severity was shown that severe hypoxia causes in lung tissue hyperhydration of air-blood barrier and expressed mitochondrial dysfunction (MD). In the myocardium, together with a thickening of histogematic barrier, in the mitochondrial apparatus of cardiomyocytes besides signs of MD occurs the formation of certain compensatory-adaptive mechanisms to maintaining an adequate energy supply of the heart. After hypoxia of average degree hyperhydration of biological barriers was absence, in the mitochondrial apparatus of the heart and lungs tissues in the absence of MD was formed some compensatory mechanisms aimed at preventing of tissue hypoxia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8f8f86c9d8595be1158421e4d784e121 https://doi.org/10.24061/2413-4260.v.2.16.2015.3 Zobrazit plný text záznamu