Phytochemical Composition of Methanolic Extract of Phyllanthus acidus L (Skeels) Fresh Leaves by GC/MS Analysis
| Autor: | Rohan Sharadanand Phatak, Pushpa Durgawale, Anup Subhash Hendre |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Phyllanthus
biology Traditional medicine 02 engineering and technology Phyllanthaceae 010402 general chemistry 021001 nanoscience & nanotechnology biology.organism_classification 01 natural sciences 0104 chemical sciences Phytochemical Phytochemical composition Maceration (wine) Pharmacology (medical) Gas chromatography–mass spectrometry 0210 nano-technology Pharmacology Toxicology and Pharmaceutics (miscellaneous) Retention time |
| Zdroj: | Research Journal of Pharmacy and Technology. 9:559 |
| ISSN: | 0974-360X 0974-3618 |
| Popis: | Background: Secondary metabolites and different phytochemicals are present in the medicinal plant Phyllanthus acidus belonging to family Phyllanthaceae. Scientific evidence data related GC-MS analysis of methanolic extract of Phyllanthus acidus fresh leaves has not been reported till date during literature review. Objective: The study was aimed to investigate phytochemicals present in the methanolic extract of Phyllanthus acidus fresh leaves. Material and Methods: Methanolic extraction of fresh leaves Phyllanthus acidus was prepared by simple maceration and GC-MS analysis data was provided by IICPT, Thanjavur. Phytochemical investigation was carried out to identify the possible components from Phyllanthus acidus fresh leaves by evaluating retention time in the GC-MS chromatogram. Results: Eleven peaks have revealed in the GC-MS spectrum of the methanolic extract of Phyllanthus acidus. From the results, squalene is present as major bioactive compounds in methanolic extract of Phyllanthus acidus fresh leaves. Conclusion: The present data provides to find the molecular formula and weight of 11 biomolecules. Further investigation should be done to isolate bioactive compounds and their structural elucidation and screening of pharmacological activity in the drug development. |
| Databáze: | OpenAIRE |
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