Phytochemical Investigation, Antioxidant and Antimicrobial Assays of Algerian Plant Calamintha baborensis Batt
| Autor: | Rofia Seraoui, Gaspar Ros, Rachid Benkiniouar, Salah Akkal, Gema Nieto |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pharmacology
Chromatography ABTS biology DPPH 010401 analytical chemistry Ethyl acetate 04 agricultural and veterinary sciences Fractionation biology.organism_classification 040401 food science 01 natural sciences Calamintha 0104 chemical sciences law.invention Eugenol chemistry.chemical_compound 0404 agricultural biotechnology chemistry law Drug Discovery Lamiaceae Essential oil |
| Zdroj: | Pharmaceutical Chemistry Journal. 52:347-356 |
| ISSN: | 1573-9031 0091-150X |
| Popis: | The aim of this work was to evaluate the antioxidant capacity of some increasing polarity soluble fractions of hydroalcoholic extract of the leaves of Algerian Lamiaceae Calamintha baborensis Batt., including hexanoic (Hex), chloroformic (Chlor), ethyl acetate (EtOAc) and n-butanolic (n-BuOH) and four subfractions (A, B, C, D) resulting from fractionation on a polyamide column. The EtOAc and n-BuOH extracts of the plant gave the highest values of antioxidant power by different methods: ABTS, percentage inhibition of 68.9/81.7%; DPPH, 27.6/80.99%; ORAC/FRAP, 37.28/28.47 and 21.73/19.52 μM/mL, respectively; IC50 values, 23 and 53.5 ppm. In addition, they were evaluated for their total phenolic content. The antibacterial activity of extracts showed good results with hexanoic and chloroformic fractions against E. coli (19 mm and 19.2 mm diameter of inhibition zone and MIC values about 43 and 43.4 μg/mL, respectively.) Apolar fractions from the leaves of C. Baborensis Batt. were analyzed by gas chromatography–mass spectrometry (GC–MS). The main components of the essential oil of C baborensis Batt. are eugenol (27.04%) and 3-methoxy acetophenone (26.4%). |
| Databáze: | OpenAIRE |
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