Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid

Autor: Seema Suvadarshini, Ipsita Aparajita Mohapatra, Sonali Dash, Soumyashree Nayak, Meenakshee Mohanty, Srimay Pradhan, Sonali Suchismita Behera, Punya Prateek Majhi, Akshaya Kumar Sahoo
Rok vydání: 2020
Předmět:
Zdroj: Journal of Pharmaceutical Research International. :94-97
ISSN: 2456-9119
Popis: Phytochemicals from Moringa oleifera plant extract can cure Typhoid. It is caused by Salmonella typhi. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 4,8,12,16-tetramethylheptadecan-4-olide can effectively deactivate the 2-hydroxy-3-oxopropionate reductase enzyme thereby interrupting the life cycle of the organism.
Databáze: OpenAIRE