Hydrophobin-stabilized nanoemulsion produced by a low-energy emulsification process: A promising carrier for nutraceuticals

Autor: Nathália Kelly de Araújo, Andreza Rochelle do Vale Morais, Matheus De Freitas Fernandes Pedrosa, Andre Ezequiel Gomes Nascimento, Iasmim Lopes de Lima, Christian Melo de Oliveira, Eryvaldo Sócrates Tabosa do Egito, Arnobio Antonio Silva-Jr., Roberto Afonso da Silva, Mariane Cajubá de Britto Lira Nogueira, Francisco Humberto Xavier-Jr.
Rok vydání: 2019
Předmět:
Zdroj: Food Hydrocolloids. 89:749-757
ISSN: 0268-005X
DOI: 10.1016/j.foodhyd.2018.11.057
Popis: Hydrophobin II (HFBII) is an amphiphilic biopolymer that could be explored to stabilize oil-in-water nanoemulsions as nutraceutical delivery systems. This study reports the production of HFBII-stabilized nanoemulsions by a spontaneous emulsification process using copaiba oil as a bioactive lipid. HFBII was isolated from a wild-type Trichoderma reesei and characterized. A 23 full factorial design with three central points was used to obtain an optimal nanoemulsion system, whose physical-chemical properties were studied under different ionic strength and pH. The peptide similarity search allowed the identification of a series of 6 ion fragments from the isolated fraction, which can be attributed to the amino acid sequences of the HFBII database. The optimal nanoemulsion system presented a nanoscale droplet size (
Databáze: OpenAIRE