501-P: Urinary C-Peptide Creatinine Ratio: A New Marker of Insulin Resistance and Diabetic Kidney Disease
| Autor: | Linong Ji, Xiaoling Cai, Yanai Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Creatinine Diabetic kidney business.industry Endocrinology Diabetes and Metabolism Urinary system Disease Type 2 diabetes medicine.disease Gastroenterology chemistry.chemical_compound Insulin resistance chemistry C peptide/Creatinine Internal medicine Internal Medicine medicine business Morning |
| Zdroj: | Diabetes. 69 |
| ISSN: | 1939-327X 0012-1797 |
| Popis: | Introduction: Urinary C-peptide creatinine ratio (UCPCR) is used to access β cell function, but rare study had explored UCPCR in conditions with insulin resistance (IR). Some studies indicated the positive correlation between diabetic kidney disease (DKD) and IR. This study aims to explore the correlation among UCPCR,IR and DKD. Methods: Chinese hospitalized patients with type 2 diabetes were included (n=1299). Fasting UCPCR was collected in the morning. We divided patients into three groups by the tertile of UCPCR, the characteristics of three groups were compared. Results: In patients with the highest tertile of UCPCR, they had the lowest percentage of male (223 [51.6%] vs.294 [68.1%] vs. 302 [70.1%], P Conclusions: UCPCR is a practical and non-invasive marker of insulin resistance and associated with increased risk of DKD and CHD. Disclosure Y. Wang: None. X. Cai: None. L. Ji: None. |
| Databáze: | OpenAIRE |
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