Evaluation of glutamate concentration transient in the synaptic cleft of the rat calyx of Held

Autor:	Harumi Harada, Ryuichi Shigemoto, Ko Matsui, Yugo Fukazawa, Naomi Kamasawa, Timotheus Budisantoso
Rok vydání:	2012
Předmět:	Synaptic cleft Physiology Synaptic augmentation Synaptic plasticity Glutamate receptor Biophysics AMPA receptor Biology Long-term depression Calyx of Held Neuroscience Postsynaptic specialization
Zdroj:	The Journal of Physiology. 591:219-239
ISSN:	0022-3751
DOI:	10.1113/jphysiol.2012.241398
Popis:	Establishing the spatiotemporal concentration profile of neurotransmitter following synaptic vesicular release is essential for our understanding of inter-neuronal communication. Such profile is a determinant of synaptic strength, short-term plasticity and inter-synaptic crosstalk. Synaptically released glutamate has been suggested to reach a few millimolar in concentration and last for
Databáze:	OpenAIRE
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