Evaluation of the Proteolytic Activity Present in Cho Cell Culture Supernatants

Autor:	C. Tans, L. Fabry, S. Wattiaux De Coninck, M. M. Gonze
Rok vydání:	1997
Předmět:	chemistry.chemical_classification Proteases Recombinant glycoprotein Chinese hamster ovary cell Biology Molecular biology law.invention Biochemistry Viral envelope chemistry law Recombinant DNA Cell culture supernatant Glycoprotein
Zdroj:	Animal Cell Technology ISBN: 9789401062732
DOI:	10.1007/978-94-011-5404-8_46
Popis:	The heterogeneity of recombinant glycoproteins expressed by CHO cells may partly result from a proteolytic activity present in cell culture supernatants. This study investigated the presence of proteases in CHO cell culture supernatants and their effects on the quality of a recombinant secreted viral envelope glycoprotein used as a model.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8f1fcd7f822a790c2a32547d14d963a9 https://doi.org/10.1007/978-94-011-5404-8_46 Zobrazit plný text záznamu