Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia

Autor: Gadhia Pankaj, Salil Vaniawala
Rok vydání: 2014
Předmět:
Zdroj: American Journal of Clinical and Experimental Medicine. 2:128
ISSN: 2330-8125
DOI: 10.11648/j.ajcem.20140206.13
Popis: In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.
Databáze: OpenAIRE