In vivo analgesic, anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic fruits extract from Daemonorops robusta Warb
| Autor: | Mir Mn Uddin, Ramiz Ahmed Sultan, Mohammad Sabbir Rahman, Talha Bin Emran, Mohammad Sh Kabir, Shahriar Ahmed |
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| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
biology 010405 organic chemistry medicine.drug_class Alkaloid fungi Analgesic Saponin Medicine (miscellaneous) Pharmacology biology.organism_classification 01 natural sciences Anti-inflammatory 0104 chemical sciences Carrageenan 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Phytochemical In vivo Daemonorops medicine Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics |
| Zdroj: | Journal of Applied Pharmaceutical Science. :104-113 |
| ISSN: | 2231-3354 |
| DOI: | 10.7324/japs.2017.70114 |
| Popis: | Objectives: The analgesic, anti-inflammatory and thrombolytic potential of Daemonorops robusta Warb, a Bangladeshi tribal medicinal plant was studied for the first time. So our aim was to evaluate analgesic, anti-inflammatory and thrombolytic activities of fruit extract of D. robusta. Methods: Fresh fruits of plant were extracted with methanol and then subjected to preliminary phytochemical screening. Analgesic activity of the extract was performed against acetic acid induced writhing, hot plate and formalin induced test. Anti-inflammatory effect was evaluated using carrageenan induced paw edema in mice. An in vitro thrombolytic model was used to check the clot lysis potential of the extract. Results: Phytochemical screening showed the presence of alkaloid, carbohydrate, flavonoids, steroid, phlobatanin and saponin. The extract exhibited significant analgesic effect (P |
| Databáze: | OpenAIRE |
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