The role of exosomal survivin in the diagnosis of breast cancer

Autor:	S Ravichandran, Mustafa Yıldırım, Hülya Çiçek, Gülper Nacarkahya, Özlem Nuray Sever, Necla Benlier, Zeliha Yıldırım, R M Madhumitha Sri
Rok vydání:	2022
Předmět:	General Medicine
Zdroj:	International Journal of Clinical Biochemistry and Research. 9:254-259
ISSN:	2394-6377 2394-6369
DOI:	10.18231/j.ijcbr.2022.049
Popis:	Breast cancer is the leading cause of death in women across the globe. The aim of this study is to compare exosomal survivin levels in breast cancer patients and healthy population. It is also to investigate the relationship between clinicopathological parameters of breast cancer and exosomal survivin levels. Patients who were diagnosed with histopathologically confirmed breast cancer and healthy volunteers were included in the study. Serum samples from patients and healthy volunteers were stored at -80℃. Exosomes were isolated from these serum samples. The integrity of the exosomes was disrupted. Survivin levels were measured by Enzyme Linked Immuno Sorbent Assay. Data on clinicopathological parameters were obtained from patient files and compared statistically.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8ec4595269b5de80d6f30cad312bf935 https://doi.org/10.18231/j.ijcbr.2022.049 Zobrazit plný text záznamu