URINARY INDICES OF RENAL DYSFUNCTION IN NEONATAL ASPHYXIA
| Autor: | Francis R Willis, Ian K. Hewitt, Corrado Minutillo |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Asphyxia
medicine.medical_specialty urogenital system business.industry Urinary system Encephalopathy Urology Urine Glomerulus (kidney) urologic and male genital diseases medicine.disease Renal tubular function medicine.anatomical_structure Endocrinology Renal tubular dysfunction Internal medicine Pediatrics Perinatology and Child Health medicine Urinary concentration medicine.symptom business |
| Zdroj: | Pediatric Research. 35:281-281 |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1203/00006450-199402000-00162 |
| Popis: | N-acetyl-glucosaminidase ( NAG ) & Beta-2-microglobulin ( B2M ) were measured in urine of term newborns to assess effects of asphyxia on renal tubular function. NAG is an enzyme found in proximal tubular cells. Its urinary concentration reflects tubule cell breakdown. B2M is produced by the liver, filtered at the glomerulus & reabsorbed by proximal tubular cells. Urine B2M levels reflect tubular dysfunction. 32 neonates made up the study group with an equal number of controls. Study babies fulfilled a diagnosis of Posthypoxic Encephalopathy according to the system of Sainat. NAG & B2M were assayed at 24–48 hours of life & at 4-6 days. There was significant difference (P |
| Databáze: | OpenAIRE |
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