Dlt operon regulates physiological function and cariogenic virulence in Streptococcus mutans
Autor: | Jingyun Du, Shan Huang, Minjing Wu, Shuai Chen, Wen Zhou, Ling Zhan, Xiaojing Huang |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Future Microbiology. 18:225-233 |
ISSN: | 1746-0921 1746-0913 |
DOI: | 10.2217/fmb-2022-0165 |
Popis: | Streptococcus mutans is one of the major cariogenic pathogens in the oral cavity. The dlt operon is responsible for the process of D-alanylation of lipoteichoic acid and is related to the virulence of S. mutans. The dlt operon contributes to the adhesion, biofilm formation, stress response, interspecies competitiveness and autolysis of S. mutans. In addition, we have summarized the possible regulatory networks of the dlt operon. This review highlights the significant role of the dlt operon in S. mutans and provides new ideas for ecological caries prevention. |
Databáze: | OpenAIRE |
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