Xeno-free, chemically defined and scalable monolayer differentiation protocol for retinal pigment epithelial cells

Autor:	Monica Aronsson, Sandra Petrus-Reurer, Hammurabi Bartuma, Sofie Westman, Emma Lardner, Emeline F. Nandrot, Anna Falk, Pankaj Kumar, Iyadh Douagi, Anders Kvanta, Sara Padrell Sánchez, Alvaro Plaza Reyes, Fredrik Lanner
Rok vydání:	2020
Předmět:	Pigment chemistry.chemical_compound Chemistry visual_art Monolayer visual_art.visual_art_medium Retinal Xeno free Cell biology
DOI:	10.21203/rs.3.pex-635/v1
Popis:	With cell therapies advancing towards the patients’ bedside, there is an increased need for robust and up-scalable protocols to generate clinical grade stem cell-derived products.The protocol we present in the study provides a xeno-free, chemically defined, scalable and robust retinal pigment epithelial cell monolayer differentiation without the need for manual isolation that uses either human embryonic stem cells or human induced pluripotent stem cells as a starting material.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8e89878173b76403ee4a5c00bc345458 https://doi.org/10.21203/rs.3.pex-635/v1 Zobrazit plný text záznamu