Synthesis and Spectral Characterization of Related Substances of Lacidipine, an Antihypertensive Drug

Autor:	Ganta Madhusudhan Reddy, P. K. Dubey, Vijayavitthal T. Mathad, V. V. N. K. V. Prasada Raju, Vedantham Ravindra, Padi Pratap Reddy
Rok vydání:	2009
Předmět:	Chromatography Lacidipine Impurity medicine.drug_class Chemistry Organic Chemistry medicine Mass spectrometry Antihypertensive drug Bulk drug High-performance liquid chromatography medicine.drug
Zdroj:	Synthetic Communications. 39:2137-2145
ISSN:	1532-2432 0039-7911
Popis:	Five related substances (impurities) were detected in lacidipine bulk drug substance by a simple high-performance liquid chromatographic method (HPLC) and were identified by liquid chromatography–mass spectrometry (LC-MS). These related substances were independently synthesized, characterized, and co-injected with the sample containing impurities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8e86d82aa24d7577466e0bf29f18d214 https://doi.org/10.1080/00397910802638560 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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