Inequitable poverty exposures in a clinical trial cohort of children with acute lymphoblastic leukemia: an opportunity to address racial and ethnic disparities in pediatric oncology

Autor: Kristine Karvonen, Puja Umaretiya, Victoria Koch, Yael Flamand, Rahela Aziz-Bose, Lenka Ilcisin, Ariana Valenzuela, Peter Cole, Lisa Gennarini, Justine Kahn, Kara Kelly, Thai Hoa Tran, Bruno Michon, Jennifer Welch, Joanne Wolfe, Lewis Silverman, Abby R. Rosenberg, Kira Bona
Rok vydání: 2023
Popis: Black and Hispanic children with leukemia experience inferior survival compared to non-Hispanic White (NHW) children. Identifying modifiable social determinants of health can inform intervention targets to address inequities. We characterized the frequency of income poverty and household material hardship (HMH) by race/ethnicity in a clinical trial cohort with de novo acute lymphoblastic leukemia. Compared to NHW families, Black and Hispanic families reported more frequent HMH (19% vs. 47% vs. 68% respectively); low-income (27% vs. 52% vs. 74%), and combined low-income and HMH (12% vs. 37% vs. 52%) poverty exposures. Disparate poverty exposures are interventional targets to address racial/ethnic outcome inequities.
Databáze: OpenAIRE