Reactions with Hydrazonoyl Halides 53:1 Synthesis and Antimicrobial Activity of Triazolino[4,3-a]pyrimidines and 5-Arylazothiazoles
Autor: | Zeineb H. Ismail, Abdou O. Abdelhamid, Marwa S. El Gendy, M. M. Ghorab |
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Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Phosphorus, Sulfur, and Silicon and the Related Elements. 182:2409-2418 |
ISSN: | 1563-5325 1042-6507 |
DOI: | 10.1080/10426500701501292 |
Popis: | 6-(2-Naphtyl)-1-phenyl-4-3,5-disubstituted 4,3a-triazolino[4,3-a]pyrimidines, [2(1-(2-naphthyl)-5-substitued (1-pyrazolin-3-yl)-4-phenyl(thiazol-5-yl)phenyldiazine and 1-(2-aza-2-[4-phenyldiazenyl)-(1,3-thiazol-2-yl)]amino}vinyl)-naphthalene-2-ol were synthesized via reactions of hydrazonoyl halides with 4-(2-naphthyl)-6-substituted 3,4-dihydropyrimidine-2-thione, Amino(3-(2-naphthyl)-5-substituted pyrazolin-2-ylmethane-1-thione, and 2-hydroxynaphthalenecarbaldehyde-thiosemicarbazone. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, and alternative synthesis methods whenever possible. Some of the new compounds were tested towards bacteria. In general, all tested compounds were capable of highly inhibiting the growth of gram positive of bacteria and gram negative. |
Databáze: | OpenAIRE |
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