The Relationship between Inflammation and Hemostasis Disorders in Cardiovascular and Infectious Diseases

Autor: Vladimir V. Bykov, Aleksandr I. Vengerovskii, Vladimir V. Udut
Rok vydání: 2022
Předmět:
Zdroj: Annals of the Russian academy of medical sciences. 77:261-266
ISSN: 2414-3545
0869-6047
Popis: Thrombosis and inflammation develop concomitantly during inflammatory, cardiovascular and infectious diseases. Thrombosis induces inflammation and immune system disruption, while inflammation leads to increased hemostasis a vascular thrombosis. Combined use of anti-inflammatory and antithrombotic drugs often leads to adverse effects, for example, nonsteroidal anti-inflammatory drugs induce gastric ulcers, aggravated by bleeding. Vascular endothelial dysfunction plays an important role in the development of thrombosis and inflammation, therefore, research and development of drugs improving endothelial function is a promising approach to preventing thrombotic events arising from inflammation or infectious disease.
Databáze: OpenAIRE