A new route to 2-styrylbenzimidazoles

Autor: Arthur Furst, Marjorie K. Balazs
Rok vydání: 1970
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 7:1381-1384
ISSN: 1943-5193
0022-152X
DOI: 10.1002/jhet.5570070624
Popis: An attempt was made to prepare 2-benzylquinoxalin-3-one by hydrolyzing the azlactone, 2-phenyl-4-benzylidene-5-oxazolone to β-phenylpyruvic acid and then treating this in situ with o-phenylenediamine (OPDA). The initial hydrolysis apparantly proceeded only as far as opening the azlactone ring forming 2-benzamidocinnamic acid which condensed with OPDA to form a substituted styrylbenzimidazole.
Databáze: OpenAIRE