Hypertensive Changes in Experimental Nephritis Combined with Experimental Hypertension

Autor: Yoshiaki Masuyama, Ichiro Nishio, Kenzo Motoki, Yoshio Kusuyama, Sho Tanaka, Mitsumasa Nagase
Rok vydání: 2015
Předmět:
Popis: The role of hypertension in chronic glomerulonephritis was studied in rats with experimental hypertension and nephrotoxic serum nephritis. Nephrotoxic serum nephritis accelerated the hypertensive course of Godblatt's type of experimental hypertension both in the acute and chronic phases. Malignant hypertension was found to be caused in some rats by the nephrotoxic serum injection in the chronic phase of experimental hypertension. Nephrotoxic serum nephritis was more protracted in SHR than in control rats. These results suggest that hypertensive changes might aggravate glomerulitis, and that nephritic processes also facilitate the hypertensive changes.
Databáze: OpenAIRE