Correlation between Urinary Bisphenol A, Serum 25 OH Vitamin D Levels and Preterm Birth in Egyptian Pregnant Women

Autor: Nermin Emam, Sahar El-Dakroory, Sara A. Mohamed, Reem Abo-Elmaaty, Adel El-Mansory
Rok vydání: 2021
Předmět:
Zdroj: Egyptian Society of Clinical Toxicology Journal. 9:21-33
ISSN: 2356-6523
Popis: Introduction: Preterm birth (PTB) is a worldwide cause of infant mortality and morbidity. Prenatal exposure to endocrine disrupting chemicals (EDCs) especially bisphenol A (BPA) is questioned as a potential risk factor for PTB. Lower gestational vitamin D levels are associated with various maternal and fetal complications. Aim of the Work: This study aimed to evaluate the gestational exposure to BPA and the potential association between urinary BPA and serum vitamin D levels in a sample of Egyptian women having spontaneous PTB. Subjects and Methods: This study was conducted on 106 reproductive aged females divided into Group I with full term delivery (37-42 weeks gestational age) as “control group” and Group II with spontaneous preterm contractions (24 - ˂37 weeks gestational age) that ended with preterm delivery as “PTB group”. Results: The median level of urinary uncorrected and specific gravity (SG)-corrected BPA was found to be higher in PTB group with high statistically significant difference between both studied groups (P
Databáze: OpenAIRE