Treatment of cardiometabolic risk factors in patients with type 1 diabetes
| Autor: | Elżbieta Niechciał, M. Loredana Marcovecchio |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Type 1 diabetes
medicine.medical_specialty endocrine system diseases business.industry Psychological intervention nutritional and metabolic diseases medicine.disease Obesity 03 medical and health sciences 0302 clinical medicine Insulin resistance 030225 pediatrics 030220 oncology & carcinogenesis Diabetes mellitus Pediatrics Perinatology and Child Health medicine Life expectancy Intensive care medicine business Dyslipidemia Glycemic |
| Zdroj: | Current Opinion in Pediatrics. 32:589-594 |
| ISSN: | 1531-698X 1040-8703 |
| DOI: | 10.1097/mop.0000000000000915 |
| Popis: | Purpose of review Individuals with type 1 diabetes (T1D) have excess cardiovascular risk and reduced life expectancy. Adolescence is the time when the first signs of vascular complications appear and a critical window for interventions. This article reviews recent evidence on cardiometabolic risk factors and their management in youth with T1D. Recent findings Adolescents with T1D show early signs of vascular complications, as a result of several cardiometabolic risk factors. Poor glycemic control is one of the main risk factors and the main target of treatment. However, only a minority of adolescents with T1D reaches recommended targets for glycemic control. Hypertension, dyslipidemia, smoking, alcohol use, obesity and insulin resistance are other common cardiometabolic risk factors in this age group. Recent data confirm that screening for these risk factors is suboptimal and use of pharmacological interventions for hypertension and dyslipidemia remains low. Data on adjunctive noninsulin agents to improve glycemic control and other cardiometabolic risk factors are still lacking in this age group. Summary Vascular complications and the associated mortality remain a major issue for youth with T1D. Better screening strategies for cardiometabolic risk factors and interventions are required to improve the long-term prognosis of youth with T1D. |
| Databáze: | OpenAIRE |
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