Effect of Histamine and Insulin on Eosinophils and Mast Cells in the Rat Gastric Mucosa1
| Autor: | Toimi Räsänen |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
0303 health sciences
medicine.medical_specialty Lamina propria Physiology Insulin medicine.medical_treatment digestive oral and skin physiology Degranulation Stimulation Mast cell 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure Endocrinology chemistry Internal medicine Immunology Gastric mucosa medicine Eosinophilia 030211 gastroenterology & hepatology medicine.symptom Histamine 030304 developmental biology |
| Zdroj: | Acta Physiologica Scandinavica. 61:205-211 |
| ISSN: | 1365-201X 0001-6772 |
| DOI: | 10.1111/j.1748-1716.1964.tb02959.x |
| Popis: | The number of mast cells in the mucosa of the glandular stomach of the rat decreased on account of degranulation 2–4 hours after histamine and insulin injections and after ingestion of food. Re-granulation of the mast cells occurred in a later phase. Morphological changes were established in the mast cell granules during gastric stimulation. Tissue eosinophilia of the lamina propria of the glandular stomach increased at the beginning of the stimulation, decreasing in a later phase. Lethal insulin shock caused an increase in the tissue eosinophilia of the glandular stomach. The role of the heparin and histamine contained in the mucosal mast cell granules during the stimulation of the gastric mucosa, in the phase in which the ion changes and local heparinemia in the mucosal lamina propria perhaps provoke inhibition of eosinolysis, is suggested. |
| Databáze: | OpenAIRE |
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