Synthesis and in vitro antibacterial activities of 7-(3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)quinolone derivatives

Autor:	Xin Guo, Yu Fei Liu, Yucheng Wang, Hui Yuan Guo, Yi Liang Li
Rok vydání:	2010
Předmět:	Levofloxacin Moxifloxacin Chemistry Gemifloxacin medicine.drug_class Stereochemistry medicine General Chemistry Quinolone In vitro Gatifloxacin medicine.drug
Zdroj:	Chinese Chemical Letters. 21:1141-1144
ISSN:	1001-8417
DOI:	10.1016/j.cclet.2010.06.011
Popis:	A series of novel 7-(3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)quinolone derivatives were designed, synthesized and evaluated for in vitro antibacterial activities. Compounds 6g, 7g and 7h with the potencies similar to those of gemifloxacin, moxifloxacin, gatifloxacin and levofloxacin against Gram-positive organisms, worth further investigation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8e4830a5832a98677abfc067177d2bbe https://doi.org/10.1016/j.cclet.2010.06.011 Zobrazit plný text záznamu Full Text from ScienceDirect