PS1 - 6. Pyridoxamine improves adiposity and insulin resistance in high-fed diet induced obese mice

Autor:	Coen D.A. Stehouwer, Olaf Brouwers, Katrien H.J. Gaens, Toshio Miyata, Casper G. Schalkwijk
Rok vydání:	2013
Předmět:	medicine.medical_specialty business.industry Adipokine Adipose tissue Type 2 diabetes medicine.disease RAGE (receptor) Insulin resistance Endocrinology Glycation hemic and lymphatic diseases Diabetes mellitus Internal medicine Medicine business Diet-induced obese
Zdroj:	Nederlands Tijdschrift voor Diabetologie. 11:145-146
ISSN:	1876-6242 1567-2743
DOI:	10.1007/s12467-013-0084-9
Popis:	Obesity is characterized by a dysregulation of pro- and anti-inflammatory adipokines which are involved in the pathogenesis of obesity-related insulin resistance and type 2 diabetes. We showed that the advanced glycation endproduct (AGE), Ne-(Carboxymethyl)lysine (CML), accumulates in adipose tissue in obesity and that CML, via the receptor for AGEs (RAGE) leads to inflammatory adipokines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8e41d171db6f5303ccee5e8f3d5431f9 https://doi.org/10.1007/s12467-013-0084-9 Zobrazit plný text záznamu Full text from SpringerLink