Flow Characteristics and Coherent Structures in a Centrifugal Blood Pump
Autor: | Lisa Prahl Wittberg, Niclas Berg, Laszlo Fuchs |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Pressure drop Materials science Membrane oxygenator General Chemical Engineering Flow (psychology) General Physics and Astronomy Mechanics 030204 cardiovascular system & hematology Centrifugal pump Vortex 03 medical and health sciences Impeller Flow separation 030104 developmental biology 0302 clinical medicine Flow conditions Physical and Theoretical Chemistry |
Zdroj: | Flow, Turbulence and Combustion. 102:469-483 |
ISSN: | 1573-1987 1386-6184 |
DOI: | 10.1007/s10494-018-9994-3 |
Popis: | Blood clot formation can be initiated by local flow conditions where regions of high shear and long residence time regions, such as flow separation and stagnation, have been identified as risk factors. This study highlights coherent structures, some of which not yet considered in the literature that may contribute to blood clot formation in the ECMO (Extra Corporeal Membrane Oxygenator) circuit. The centrifugal ECMO pump investigated in this study is compact and delivers adequate volume of blood with relatively high pressure in order to compensate for the large pressure drop in the membrane oxygenator. These requirements lead to regions with high shear in several different parts of the pump. In the narrow gap between the pump house and the impeller body (the magnet) a Taylor-Couette-like flow is observed with azimuthally aligned wavy vortices, which are also pushed towards the bottom of the pump-house by the flow generated by the blades. At the bottom gap between the impeller house and the pump house one finds spiraling flow structures, due to the rotation of the former structure. Separation bubbles are found near the tongue of the pump and at the lee sides of the blades. Such vortical structures have in literature been identified as regions where platelets may be activated whereby clots may develop. |
Databáze: | OpenAIRE |
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