Association between endoscopic findings related to colonic diverticula and bowel habits: A multicenter study in Japan
| Autor: | Yutaka Isozaki, Ken Haruma, Yukihiro Ozawa, Noriaki Manabe, Yasuo Hata, Yoriko Murata, Hirokazu Oyamada, Masahiko Inamori, Eiji Yamada, Hitoshi Kuriyama, Akira Mizuki, Atsushi Nakajima, Takafumi Ito, Eri Uchida, Masataka Tagri |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Constipation Hepatology medicine.diagnostic_test Bowel habit business.industry Gastroenterology Sigmoid colon Mean age Colonic Diverticulum digestive system digestive system diseases Endoscopy 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Multicenter study 030220 oncology & carcinogenesis Internal medicine medicine 030211 gastroenterology & hepatology medicine.symptom Multiple colonic diverticula business |
| Zdroj: | Journal of Gastroenterology and Hepatology. 32:1938-1942 |
| ISSN: | 0815-9319 |
| Popis: | Background and Aim Few studies have shown the associations between colonic diverticula and endoscopic findings such as location, inflammation, number of diverticula, sigmoid colon rigidity, and bowel habits. Methods Japanese subjects who underwent total colonoscopies at six centers in Japan from November 2015 to October 2016 were analyzed. Bowel habits were evaluated using the Gastrointestinal Symptom Rating Scale. Location and number of diverticula, inflammation, and sigmoid colon rigidity were evaluated from endoscopy results. Results A total of 762 subjects (486 men and 276 women [ratio, 1.76:1]) whose mean age was 65.5 ± 11.4 years were evaluated. In multivariate analysis, presence of constipation was associated with a significantly lower likelihood of left-sided colonic diverticula (odds ratio = 0.40, 95% confidence interval 0.20–0.82, P = 0.012), whereas right-sided and bilateral-sided colonic diverticula, multiple colonic diverticula, inflammation findings, and sigmoid colon rigidity were not related to bowel habits. Conclusions Among endoscopic findings related to colonic diverticula and bowel habits, only left-sided colonic diverticula were inversely associated with constipation, whereas inflammation findings, multiple diverticula, and sigmoid colon rigidity were not related to bowel habits. However, the association of inflammation findings with colonic diverticula and bowel habits should be further studied. Investigation of changes in left-sided colonic diverticula may lead to new treatments for constipation. |
| Databáze: | OpenAIRE |
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