Quantitative Evaluation of Different Dosage Forms of Ampicillin

Autor: Mohammad K. Hassanzadeh
Rok vydání: 1991
Předmět:
Zdroj: Drug Development and Industrial Pharmacy. 17:1795-1810
ISSN: 1520-5762
0363-9045
Popis: The bioavailability of five different commercial brands of ampicillin was examined. The absorption of each dosage form was compared in a crossover study of twelve healthy volunteers (6 males and 6 females). Urinary excretion rates were also employed to evaluate the absorption process. Statistical analysis of the results was carried out to evaluate the significance of differences between dosage forms and subjects. The statistical analysis indicated no significant differences between different tested brands of ampicillin, while the differences between subjects were significant. Comparison between the two different genders indicated no significant differences between the male and female subjects.
Databáze: OpenAIRE