Direct synthesis of functionalized 3-pyrrolidines and 4-piperidines using the borrowing hydrogen methodology
| Autor: | Malvina Larduinat, Jordan François, Maiwenn Jacolot, Florence Popowycz |
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| Rok vydání: | 2023 |
| DOI: | 10.26434/chemrxiv-2023-ctmh2 |
| Popis: | The Ir(III)-catalyzed synthesis of 3-pyrrolidinols and 4-piperidinols combining 1,2,4-butanetriol or 1,3,5-pentanetriol with primary amines was carried out. This borrowing hydrogen methodology (BH) was further extended to the sequential diamination of triols leading to aza-pyrrolidines and aza-piperidines |
| Databáze: | OpenAIRE |
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