Analgesic, anxiolytic and sedative-like activities of leaves of Alpinia calcarata Roscoe in mice
| Autor: | Farjana Yeasmin, and Mohammad Anwarul Basher, A. F. M. Shahid Ud Daula, Mahmuda Ferdous, Shahnaz Naznin |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
Elevated plus maze Traditional medicine 010405 organic chemistry medicine.drug_class Chemistry Analgesic Pharmaceutical Science Plant Science 01 natural sciences Anxiolytic Open field 0104 chemical sciences 010404 medicinal & biomolecular chemistry Complementary and alternative medicine In vivo Sedative Drug Discovery medicine Alpinia calcarata Licking |
| Zdroj: | Journal of Medicinal Plants Research. 14:155-163 |
| ISSN: | 1996-0875 |
| DOI: | 10.5897/jmpr2020.6913 |
| Popis: | The objectives of the study were to evaluate the analgesic, anxiolytic and sedative-like activities of methanol extract of leaves of Alpinia calcarata Roscoe in mice model. Analgesic activity was investigated using the acetic acid-induced writhing test and formalin-induced paw licking test. In vivo neuropharmacological effects, including anxiolytic and sedative effects were examined by open field, light-dark, elevated plus maze, thiopental sodium-induced sleeping time and hole cross tests behaviors in mice. The extract produced significant (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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