Follow-up results of an ECOG study of adjuvant therapy in post-menopausal women with breast cancer

Autor:	H. C. Falkson, Robert Gray, W. H. Wolberg, G. Falkson
Rok vydání:	1994
Předmět:	Oncology medicine.medical_specialty Chemotherapy business.industry medicine.medical_treatment Disease medicine.disease law.invention Breast cancer Randomized controlled trial Hormone receptor law Internal medicine Adjuvant therapy Medicine business Adjuvant Tamoxifen medicine.drug
Zdroj:	Cancer Treatment An Update ISBN: 9782817807676
DOI:	10.1007/978-2-8178-0765-2_30
Popis:	In 1982 the Eastern Cooperative Oncology Group started a prospectively controlled, randomized trial in postmenopausal women with operable node positive breast cancer. The aim of the study was to compare the adjuvant efficacy of 4 cycles versus 12 cycles of chemotherapy as well as to evaluate the effect of long-versus short-term Tamoxifen. This is the first study directly evaluating the importance of Tamoxifen duration in an adjuvant setting. In addition to investigating duration of adjuvant treatment, the study was also designed to investigate the impact of pretreatment patient characteristics, namely the number of involved nodes and the hormone receptor status of the tumor, on disease-free interval and disease recurrence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8dd0532c337517e347ecb962a96cf2da https://doi.org/10.1007/978-2-8178-0765-2_30 Zobrazit plný text záznamu