Asymmetric Reactions Catalyzed by Chiral Metal Complex. LXII. Efficient Asymmetric Hydrogenation of Imines Catalyzed by a Neutral Iridium(I) Complex of (4R,5R)-MOD-DIOP

Autor:	Noriya Nakajima, Kazuo Achiwa, Toshiaki Morimoto
Rok vydání:	1994
Předmět:	Bicyclic molecule Asymmetric hydrogenation Imine Enantioselective synthesis chemistry.chemical_element General Chemistry General Medicine Medicinal chemistry Catalysis chemistry.chemical_compound Benzylamine chemistry Drug Discovery Iridium Efficient catalyst
Zdroj:	Chemical and Pharmaceutical Bulletin. 42:1951-1953
ISSN:	1347-5223 0009-2363
Popis:	A neutral iridium(I) complex of (4R, 5R)-MOD-DIOP (1b) was found to be an efficient catalyst for the asymmetric hydrogenation of imines, N-(α-methylbenzylidene)benzylamine (4) and 2, 3, 3-trimethylindolenine (6), in the presence of tetrabutylammonium iodide. A high enantioselectivity with up to 81.4% ee was achieved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8dc4a61c097575cc3fec4091914ca80d https://doi.org/10.1248/cpb.42.1951 Zobrazit plný text záznamu