Stabilization of silver nanoparticles in chitosan and gelatin hydrogel and its applications

Autor: Phong A. Tran, Tran Ngoc Quyen, Thi-Hiep Nguyen, Vo Van Toi, Nhi Tra Thanh, Nghi Thi-Phuong Nguyen, Hui-Min David Wang, Long Vuong-Hoang Nguyen
Rok vydání: 2019
Předmět:
Zdroj: Materials Letters. 248:241-245
ISSN: 0167-577X
DOI: 10.1016/j.matlet.2019.03.103
Popis: This study aims to investigate the effect of chitosan and gelatin as a stabilizer of silver nanoparticles (Ag NPs) and on their application designs. Ag NPs hydrogels was synthesized and stabilized by capping agents (chitosan and gelatin). Then, Ag NPs membrane was prepared by coating Ag NPs hydrogel on PCL fibrils. Optical and microscopic observation as well as structural properties were studied to compare two stabilizers. Antimicrobial testing was done on both Ag NPs hydrogels and membranes. The results suggest that gelatin provides better stabilizing activity and superior antimicrobial potency in membrane form while chitosan exhibits better antibacterial inhibition in hydrogel form.
Databáze: OpenAIRE