Molecular epidemiology ofFonsecaea pedrosoiusing mitochondrial DNA analysis

Autor: Masanori Aoki, R. Negroni, M. Mendonca, C De Vroey, Phillippe Esterre, Makoto Miyaji, K. Nishimoto, Masako Kawasaki, A. Andriantsimahavandy, Kazuko Nishimura, T. Matsumoto, Hiroshi Ishizaki
Rok vydání: 1999
Předmět:
Zdroj: Medical Mycology. 37:435-440
ISSN: 1460-2709
1369-3786
DOI: 10.1080/mmy.37.6.429.440
Popis: Restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) from 49 clinical Fonsecaea pedrosoi isolates (18 isolates from Japan, 17 from Madagascar, 7 from Argentina, 5 from Venezuela, 1 from Costa Rica and 1 unknown) was studied. The 49 isolates were composed of 20 isolates of Type 1, 16 of Type 2, 12 of Type 4 and 1 of a new mtDNA type, Type 7, which was closely related to Type 2. On the bases of the results of 120 isolates of the present (49 isolates) and previous (71 isolates) studies, F. pedrosoi was classified into seven mtDNA types and according to the relationship between mtDNA types and geographic origins: in Japan and probably in China, Type 1 isolates; in Zaire and Madagascar, Type 2; in Central and South America, Type 4 and Type 1. These results indicated that the geographical origin of F. pedrosoi isolate could be roughly inferred from its mtDNA type.
Databáze: OpenAIRE