Outcome in neonates with congenital heart disease referred for respiratory extracorporeal membrane oxygenation
| Autor: | Aparna Hoskote, Allan Goldman, Katherine L Brown, Deborah Ridout, Fiona Miles, Ian D. Sullivan, Linda Verhulst |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pediatrics Heart disease business.industry medicine.medical_treatment Respiratory disease General Medicine medicine.disease Cardiac surgery surgical procedures operative Respiratory failure Great arteries Intensive care Pediatrics Perinatology and Child Health medicine Extracorporeal membrane oxygenation Coronary care unit business |
| Zdroj: | Acta Paediatrica. 94:1280-1284 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.2005.tb02089.x |
| Popis: | Aim: To evaluate the proportion of neonates referred for extracorporeal membrane oxygenation (ECMO) support in the modern era of advanced conventional treatments for respiratory failure who actually had congenital heart disease (CHD), and to assess the impact of this diagnostic route on patient condition and outcome. Methods: A retrospective case-note review of neonatal ECMO and cardiac admissions to a single, tertiary ECMO and cardiac intensive care unit (ICU) between March 1999 and February 2002. Results: 287 symptomatic neonates presented to the ICU with previously undiagnosed cardiac or respiratory disease. Eighty-two with presumed respiratory failure were referred for ECMO, and 205 with suspected CHD were referred for cardiac evaluation. Eight (10%) ECMO referrals, all with presumed persistent pulmonary hypertension of the newborn (PPHN), were found to have CHD (transposition: 3; total anomalous pulmonary venous connection: 3; left heart obstructive lesions: 2). Mortality in this group was 50%, compared with 11% for correctly identified CHD patients (odds ratio 8.2, 95% CI 1.92, 35.4, p |
| Databáze: | OpenAIRE |
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