Synthesis and Antibacterial Activity of Novel N-Methyl Pyrrolidine Dendrimers via [3+2] Cycloaddition

Autor:	Perumal Rajakumar, Sebastian Raja, Ayyavu Thirunarayanan
Rok vydání:	2014
Předmět:	Chalcone biology Stereochemistry fungi General Physics and Astronomy Azomethine ylide Bacillus subtilis biology.organism_classification Pyrrolidine Cycloaddition chemistry.chemical_compound chemistry Dendrimer Moiety Antibacterial activity
Zdroj:	Proceedings of the National Academy of Sciences, India Section A: Physical Sciences. 84:371-379
ISSN:	2250-1762 0369-8203
DOI:	10.1007/s40010-013-0120-6
Popis:	One-pot synthesis of novel N-methyl pyrroli- dine dendrimers has been accomplished in good yield via a facile (3?2) cycloaddition of azomethine ylide with chal- cone moiety of the dendrimer as a dipolarophile. All the pyrrolidine dendrimers exhibited moderate and comparable antibacterial activity as that of the standard viz., chloram- phenicol against Bacillus subtilis, E. coli, Klebsiella pneumoniae and species of Streptococcus by agar well diffusion method.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8d92beefaf0cf0b86478bfde8f3ceea0 https://doi.org/10.1007/s40010-013-0120-6 Zobrazit plný text záznamu Full text from SpringerLink