39. EEG and multimodal evoked potential studies in children with leukodystrophies
| Autor: | M. Di Capua, Enrico Bertini, M. Fraietta, S. Pro, R. Miliucci |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Heterogeneous group medicine.diagnostic_test Disease Electroencephalography Audiology medicine.disease Pyramidal signs Sensory Systems White matter medicine.anatomical_structure Degenerative disease Neurology Physiology (medical) medicine Neurology (clinical) Evoked potential Psychology Erg Neuroscience |
| Zdroj: | Clinical Neurophysiology. 128:e424 |
| ISSN: | 1388-2457 |
| DOI: | 10.1016/j.clinph.2017.09.046 |
| Popis: | Leukodystrophies are a heterogeneous group of white matter degenerative disease characterized by variable clinical presentation. A specific neurophysiological profile of the different leukodystrophies has not yet been established. We investigated EEG and multimodal-EPs in various leukodystrophies, to determinate their possible role as an aid in differential and early diagnosis. 49-children were studied. From the current data, PEV (50%) and BAEPs (49%) appear among the most valuable tools, particularly in the first evaluation; EEG is extremely sensible (74%) but in long term disease; ENG is useful only in well known leukodystrophies; SEP was altered in 38% while MEP in 100% of pts (all with clear clinical pyramidal signs), ERG was altered only in 1 pt. In conclusion PEV and BAEPs appear useful in the early stages of disease, EEG in long term disease, while ENG only in selected cases. The other tools have ancillary role without clear utility. |
| Databáze: | OpenAIRE |
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