Muscle fiber recovery functions studied with double pulse stimulation
| Autor: | Jože V. Trontelj, Marjan Mihelin, Erik Stålberg |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Denervation
medicine.medical_specialty Muscle Denervation medicine.diagnostic_test Physiology Refractory period Chemistry Stimulation Anatomy Electromyography medicine.disease Double pulse Cellular and Molecular Neuroscience Physiology (medical) Internal medicine medicine Cardiology Neurology (clinical) Muscle fibre Muscular dystrophy |
| Zdroj: | Muscle & Nerve. 14:739-747 |
| ISSN: | 0148-639X |
| Popis: | Direct electrical stimulation with paired pulses at varied intervals was used to study the propagation velocity and action potential amplitude recovery functions (VRF and ARF) of single muscle fibers. Following a subnormal period with slowed conduction, most of the muscle fibers tested in healthy subjects showed a period of supernormal propagation velocity starting at 3 to 12 ms, with a peak between about 5 and 15 ms, a mean increase of 7%, and an approximately logarithmic decay toward 1 second. The onset of supernormality was earlier in muscle fibers from patients with muscular dystrophy and significantly delayed in those from denervated muscles. Denervated muscle fibers also had a significantly longer refractory period. |
| Databáze: | OpenAIRE |
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