Haemorheological components in the pre-geriatric and geriatric age range in a randomly selected Western Sicily population sample (Casteldaccia study)

Autor: R Cordova, G. Alletto, R. De Simone, V. Di Garbo, A. Strano, A V Panno, Giandomenico Bompiani, Gino Avellone, G. Raneli
Rok vydání: 1993
Předmět:
Zdroj: Clinical Hemorheology and Microcirculation. 13:83-92
ISSN: 1386-0291
DOI: 10.3233/ch-1993-13111
Popis: {Received 24.8.1992; accepted 7.12.1992} On a randomly selected western Sicily population sample (Casteldac­ cia Study: 600 subjects; 300 males and 300 females) of an age range from 40 to 79 years, were determined: Haematocrit (Htc) , blood vi­ scosity, plasma viscosity, filterability of whole blood and fibrinogen. Par­ ticipation was 97%, being 582 subjects (M = 287, F = 295). All the parameters measured showed a progressive increase with age and si­ gnificant differences were found between male and female subjects: Htc and blood viscosity were higher in male subjects (p < 0.01), while plasma viscosity, whole blood filterability and fibrinogen were higher in female subjects (p < 0.05). In subjects who smoke, compared to non­ smokers, all the haemorheological variables had significantly higher values (p < 0.005). Analysis of simple linear regressions showed a posi­ tive correlation between Htc and blood viscosity (r = 0.80), between plasma viscosity and fibrinogen (r = 0.81), between filterability and fibrinogen (r = 0.59) and between plasma viscosity and filterability (r = 0.64). Fibrinogen, plasma viscosity and filterability of whole blood were positively correlated with age (r = 0.37, r = 0.46, r = 0.41 respec­ tively). The authors conclude that the measurement of haemorheologi­ cal variables is a necessary for the assessment of cardiovascular risk, especially in subjects in age range 40-79 years.
Databáze: OpenAIRE