Agar-based phantoms for skin diagnostic imaging

Autor: Janis Spigulis, Anna Maslobojeva, Laura Dambite, Ilona Kuzmina, Uldis Rubins, Vanesa Lukinsone, Ilze Osina
Rok vydání: 2020
Předmět:
Zdroj: Tissue Optics and Photonics.
DOI: 10.1117/12.2555674
Popis: Agar-based skin phantoms with different thicknesses and hemoglobin concentration were evaluated for diagnostics of skin lesions by RGB imaging. Scattering properties of the phantoms were simulated using intralipid, absorption properties – using lyophilized powder of human hemoglobin. RGB images of phantoms were captured by self-developed laboratory made devices. The algorithm for calculation of chromophore concentrations are based on Beer-Lambert law and includes the photon path length evaluated from the measured photon-time-of-flight signals. Optical properties and chromophore concentration maps of phantoms obtained from RGB images were analyzed. The influence of chromophore concentration on scattering and absorption, photon path length and chromophore maps are discussed.
Databáze: OpenAIRE