An efficient procedure for the preparation of chiral β-substituted (E)-crotylsilanes: Application of a rhodium(II) catalyzed silylformylation of terminal alkynes

Autor:	Nareshkumar F. Jain, Pier F. Cirillo, Jennifer V. Schaus, James S. Panek
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Stereochemistry Aryl Organic Chemistry Perfluorobutyrate chemistry.chemical_element Alkyne Biochemistry Rhodium Stereocenter Catalysis chemistry.chemical_compound chemistry Drug Discovery Stereoselectivity Alkyl
Zdroj:	Tetrahedron Letters. 36:8723-8726
ISSN:	0040-4039
DOI:	10.1016/0040-4039(95)01894-n
Popis:	Functionalized β-substituted ( E )-crotylsilanes ( R )-7 and ( S )-8, bearing an alkyl or aryl group adjacent to the stereogenic C-Si center have been synthesized in an efficient four-step procedure initiated with a regio- and stereoselective silylformylation of a terminal alkyne catalyzed by dirhodium(II) perfluorobutyrate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8d2fe3b660bf52c630a7bcabb771c094 https://doi.org/10.1016/0040-4039(95)01894-n Zobrazit plný text záznamu Full Text from ScienceDirect