Relationship between the expressions of survivin and the prognostic related factors in breast cancer

Autor:	Xiao-xia Zhao, Xiao-juan Wang, He-ba-te Su, Jing-hua Shen, Ge-si Tao
Rok vydání:	2005
Předmět:	Oncology Related factors Cancer Research Prognostic factor medicine.medical_specialty business.industry Estrogen receptor medicine.disease Breast cancer Medicine public health Internal medicine Survivin medicine Immunohistochemistry skin and connective tissue diseases business neoplasms
Zdroj:	Chinese Journal of Cancer Research. 17:270-272
ISSN:	1993-0631 1000-9604
DOI:	10.1007/s11670-005-0024-3
Popis:	Objective: To study the relationship between the Survivin expression and the histological grade, status of ER, expression of PS2 and the prognosis of patients with primary invasive breast cancer. Method: By using LSAB and SP immunohistochemical method, the expression of Survivin, PS2 and ER in 95 cases of invasive breast cancer were detected. Results: the positive rate of Survivin was 70.5% (67/95) and the expression of Survivin was positively related to the histological grade and status of PS2 and ER. The survival time after operation of patients without expression of Survivin was longer than those with positive Survivin. Conclusion: These data suggest that Survivin expression may be considered as a new unfavorable prognostic factor of breast cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8d20bb6fcf83644188b275536b0721f6 https://doi.org/10.1007/s11670-005-0024-3 Zobrazit plný text záznamu Full text from SpringerLink