In-situ-generation of alkylsilyl peroxides from alkyl hydroperoxides and their subsequent copper-catalyzed functionalization with organosilicon compounds
| Autor: | Qin Yang, Weiping Xu, Keiji Maruoka, Terumasa Kato, Wenfeng Zhong, Yan Liu |
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| Rok vydání: | 2021 |
| Předmět: |
inorganic chemicals
chemistry.chemical_classification In situ Base (chemistry) 010405 organic chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Drug Discovery Polymer chemistry Halogen Surface modification Amine gas treating Alkyl Bond cleavage Organosilicon |
| Zdroj: | Tetrahedron Letters. 75:153144 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2021.153144 |
| Popis: | Alkylsilyl peroxides were generated in situ from the corresponding alkyl hydroperoxides using organosilicon compounds of the type Me3SiX (X = CN, N3, and halogens) and an amine base. Subsequent in situ copper-catalyzed homolytic cleavage of the alkylsilyl peroxides afforded alkyl radicals, which were then trapped with X (X = CN, N3, and halogens) to furnish products with new carbon-carbon, carbon-nitrogen, or carbon-halogen bonds in good to high yields. |
| Databáze: | OpenAIRE |
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