| Autor: |
Anita Ljubicic, Melita Jeric, Bojana Butorac Petanjek, Nataša Karamarkovic Lazarušic |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
5.2 Monitoring Airway Disease. |
| DOI: |
10.1183/13993003.congress-2016.pa3441 |
| Popis: |
Aim: The study aims to present the relation between positive outcome of bronchodilator testing (BDT) and positive bronchoprovocative methacholine challenge testing (BPT) in 282 patients that were diagnosed under the suspicion of asthma, but with normal basal spirometry. Methods: Spirometry with bronchodilator test with salbutamol (400µg) and bronchoprovocative methacholine challenge testing were performed in all patients. The methacholine test was considered positive at PC 20 FEV1 Results: Out of 282 patients, 100 were male (35.5%), the number of smokers was 33 (11.7%). The average value of basal FEV 1 expressed as mean was 101±13.3 percent of reference value. The frequency of positive BPT was diagnosed in 142 out of 282 cases (50.4 %). The frequency of positive BDT was diagnosed in 50 out of 282 cases (17.7 %). In 113 subjects with positive methacholine challenge tests the BDT was negative (79.6%). Out of 50 positive BDT subjects only in 29 patients (20.4% of all methacholine positive cases) were found positive methacholine challenge tests and in 21 patients (42%) were found negative. In 119 cases (42%) with suspected asthma symptoms BPT and BDT were both negative. While the frequency of positive BDT in different age categories didn9t reach significance level (P th year of life. Conclusion: Observed differences in BDT and BPT in cases of suspected asthma and its clinical implications indicate the need for further research especially of influence of ageing on respiratory system. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
