| Autor: |
H. Alex Bradford, Walter Ling, Neil B. Haas |
| Rok vydání: |
1981 |
| Předmět: |
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| Zdroj: |
Drug Dependence and Alcoholism ISBN: 9781468436167 |
| DOI: |
10.1007/978-1-4684-3614-3_116 |
| Popis: |
On the eve of Phase III naltrexone investigation, it seems appropriate to recall that it was almost excatly three and one-half years ago when the first naltrexone investigators’ conference was convened in this very city. We were preparing to launch the Phase II study and there was great excitement and considerable anxiety as we gathered to hear Drs. Martin, Resnick and others relate their early experience with narcotic antagonists. The questions then were whether a naltrexone study was clinically feasible, whether it would prove safe, whether it would be acceptable, and whether we could arrive at some preliminary indication of its clinical efficacy. Summarized in the preceding report were the results of a concerted effort in the intervening three years by many investigators and others associated with these projects. We have answered some of the questions and raised new ones. It seems apropos to review this experience as we prepare for the next steps in the clinical development of naltrexone. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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